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Evidence for a novel Entamoeba histolytica lectin activity that recognises carbohydrates present on ovalbumin - ScienceDirect.com

[unable to retrieve full-text content] Evidence for a novel Entamoeba histolytica lectin activity that recognises carbohydrates present on ovalbumin    ScienceDirect.com

Sepsis - World Health Organization (WHO)

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Key facts Sepsis is one of the most frequent causes of death worldwide, but there are challenges in collecting reliable data at the population level (1). From data published in 2020, there were 48.9 million cases and 11 million sepsis-related deaths worldwide, representing 20% of all global deaths ( 2). Almost half (20 million) of all estimated sepsis cases worldwide occurred in children under 5 years of age. For every 1000 hospitalized patients, an estimated 15 patients will develop sepsis as a complication of receiving health care. While sepsis can affect any individual worldwide, significant regional disparities in incidence and mortality exist with the highest rates in lower-middle-income countries (LMICs) (2). Sepsis is costly; the average hospital-wide cost of sepsis was estimated to be more than US$ 32 000 per patient in high-income countries (3) . Overview Sepsis is a life-threatening condition that happens when the body's immune system h

Cobb & Douglas Public Health Seeks Proposals for $25K Community Health Improvement Grants - Hoodline

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Calling all community health warriors in Cobb and Douglas Counties – it's time to step up and vie for a slice of public health funding. Cobb & Douglas Public Health announced they're now accepting applications for the 2024-25 Community Health Improvement Plan (CHIP) Partnership Grants, and they're keen to disperse funds to initiatives ready to make a real difference in local health issues. It's not just pocket change, either. With grant offerings of up to $25,000 per agency, those with matching funds can see their health-improving visions become reality. For projects costing $5,000 or less, applicants won't even need matching funds, a move likely to entice smaller, but equally pivotal, community initiatives. These grants target two key areas: Access to Health Services and Basic Needs, and Healthy Lifestyles, both identified by Cobb2020 and Live Healthy Douglas as critical for community health over the next few years. But make no mistake, these grants aren&

Histological validation of in-vivo larvicidal efficacy of marine Streptomyces sp. RD06 secondary metabolites against ... - ScienceDirect.com

[unable to retrieve full-text content] Histological validation of in-vivo larvicidal efficacy of marine Streptomyces sp. RD06 secondary metabolites against ...    ScienceDirect.com

Helicobacter pylori infection in infant rhesus macaque monkeys is associated with an altered lung and oral microbiome ... - Nature.com

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Abstract It is estimated that more than half of the world population has been infected with Helicobacter pylori . Most newly acquired H. pylori infections occur in children before 10 years of age. We hypothesized that early life H. pylori infection could influence the composition of the microbiome at mucosal sites distant to the stomach. To test this hypothesis, we utilized the infant rhesus macaque monkey as an animal model of natural H. pylori colonization to determine the impact of infection on the lung and oral microbiome during a window of postnatal development. From a cohort of 4–7 month-old monkeys, gastric biopsy cultures identified 44% of animals infected by H. pylori . 16S ribosomal RNA gene sequencing of lung washes and buccal swabs from animals showed distinct profiles for the lung and oral microbiome, independent of H. pylori infection. In order of relative abundance, the lung microbiome was dominated by the phyla Proteobacteria, Firmicutes, Bacteroid

Emerging infectious disease surveillance using a hierarchical diagnosis model and the Knox algorithm | Scientific ... - Nature.com

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Abstract Emerging infectious diseases are a critical public health challenge in the twenty-first century. The recent proliferation of such diseases has raised major social and economic concerns. Therefore, early detection of emerging infectious diseases is essential. Subjects from five medical institutions in Beijing, China, which met the spatial-specific requirements, were analyzed. A quality control process was used to select 37,422 medical records of infectious diseases and 56,133 cases of non-infectious diseases. An emerging infectious disease detection model (EIDDM), a two-layer model that divides the problem into two sub-problems, i.e., whether a case is an infectious disease, and if so, whether it is a known infectious disease, was proposed. The first layer model adopts the binary classification model TextCNN-Attention. The second layer is a multi-classification model of LightGBM based on the one-vs-rest strategy. Based on the experimental results, a threshold of 0.5 is selected