Introduction The scalp surface provides a distinct microenvironment to the microbes, primarily arising from the host physiological conditions, which include the sebum content, moisture, pH, and topography (Oh et al., 2014; Xu et al., 2016). Microbial communities confer advantageous survival on host surfaces, such as the cutaneous sites through different regulatory processes, including biofilm formation and quorum sensing (Brandwein et al., 2016). Thus, it is intended that the metabolic exchanges between the scalp surface and the microbiome typically support the growth of microbial biofilms in a symbiotic, commensal, or pathogenic form (Oh et al., 2014; Brandwein et al., 2016). A dysbiosis in the cutaneous microbiome has been reported in the case of dandruff, seborrheic dermatitis, and atopic dermatitis (Park et al., 2012; Clavaud et al., 2013; Chng et al., 2016; Tanaka et al., 2016). However, the scalp microbiome studies conducted so far have focused only on determining the taxonom